Generalized Prediction-Powered Inference, with Application to Binary Classifier Evaluation
Runjia Zou, Daniela Witten, Brian Williamson
TL;DR
This paper generalizes Prediction-Powered Inference (PPI) from M-estimators to any regular ALE, enabling rectified inference using unlabeled data to reduce variance while remaining computationally simple. It integrates missing-data and semiparametric efficiency insights, showing PPI does not generally attain the semiparametric efficiency bound but can serve as a practical alternative, and extends the method to handle three covariate-shift targets via IPW, IOW, and their combinations. The framework is specialized to binary classifier metrics (TPR, FPR, AUC) and validated through extensive simulations and a wine-quality case study, demonstrating variance reductions and reliable coverage when a useful predictions model is available. Collectively, the approach offers a scalable, flexible toolkit for improving inference under partially labeled data and distribution shift without requiring full derivations of efficient influence functions.
Abstract
In the partially-observed outcome setting, a recent set of proposals known as "prediction-powered inference" (PPI) involve (i) applying a pre-trained machine learning model to predict the response, and then (ii) using these predictions to obtain an estimator of the parameter of interest with asymptotic variance no greater than that which would be obtained using only the labeled observations. While existing PPI proposals consider estimators arising from M-estimation, in this paper we generalize PPI to any regular asymptotically linear estimator. Furthermore, by situating PPI within the context of an existing rich literature on missing data and semi-parametric efficiency theory, we show that while PPI does not achieve the semi-parametric efficiency lower bound outside of very restrictive and unrealistic scenarios, it can be viewed as a computationally-simple alternative to proposals in that literature. We exploit connections to that literature to propose modified PPI estimators that can handle three distinct forms of covariate distribution shift. Finally, we illustrate these developments by constructing PPI estimators of true positive rate, false positive rate, and area under the curve via numerical studies.
