Minimum Variance Designs With Constrained Maximum Bias
Douglas P. Wiens
TL;DR
The paper develops a minimax robustness framework for regression design under model misspecification by decomposing the integrated mse into a variance term and a bias term. It introduces the tuning parameter $\nu$ and the objective $I_\nu(\xi) = (1-\nu) \mathrm{var}(\xi) + \nu \mathrm{maxbias}(\xi)$, proving that the minimax designs are exact solutions $\xi_\nu = \arg\min_\xi I_\nu(\xi)$ and that these designs simultaneously solve two constrained problems: minimize integrated predictor variance with a max-bias bound $b^2$ (rbb) and minimize max bias with a variance bound $s^2$ (rbv). Theoretical results show $\xi_0$ is $I$-optimal and $\xi_1$ is uniform, with $\nu$-indexed designs bridging the two extremes; conversely any minimax design arises from an appropriate bound pair. The paper also provides practical guidance for implementing continuous minimax designs in discrete settings via rounding, along with numerical examples for straight-line and quadratic regression that illustrate the tradeoffs and guide tunings via a coefficient of maximum bias $\mathrm{cmb}(\nu)$.
Abstract
Designs which are minimax in the presence of model misspecifications have been constructed so as to minimize the maximum, over classes of alternate response models, of the integrated mean squared error of the predicted values. This mean squared error decomposes into a term arising solely from variation, and a bias term arising from the model errors. Here we consider of designing so as to minimize the variance of the predictors, subject to a bound on the maximum (over model misspecifications) bias. We consider as well designing so as to minimize the maximum bias, subject to a bound on the variance. We show that solutions to both problems are given by the minimax designs, with appropriately chosen values of their tuning constants. Conversely, any minimax design solves each problem for an appropriate choice of the bound on the maximum bias or variance.
