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On treating right-censoring events like treatments

Lan Wen, Aaron L. Sarvet, Jessica G. Young

TL;DR

The paper addresses how to handle right-censoring events in causal inference without requiring the elimination of all censoring to define estimands. It introduces a unified framework that distinguishes nuisance from non-nuisance right-censoring, formalizes two estimands $\Psi_1^g=E(Y_k^{g,\bar{\mathbf{c}}=0})$ and $\Psi_2^g=E(Y_k^{g})$, and derives identification results under models $\mathcal{M}_1$ and $\mathcal{M}_2$, clarifying when these estimands coincide. It connects the causal framework to classical survival analysis via conditional independent $\Delta_k$ and discusses identity slippages when censoring interacts with outcomes. The work guides practitioners in selecting appropriate estimands and applying g-formula or proxy-based methods, with sensitivity analyses and extensions to broader estimands. Overall, it provides a principled approach to incorporating right-censoring into causal estimands rather than treating it solely as missing data.

Abstract

In causal inference literature, potential outcomes are often indexed by the "elimination of all right-censoring events," leading to the perception that such a restriction is necessary for defining well-posed causal estimands. In this paper, we clarify that this restriction is not required: a well-defined estimand can be formulated without indexing on the elimination of such events. Achieving this requires a more precise classification of right-censoring events than has historically been considered, as the nature of these events has direct implications for identification of the target estimand. We provide a framework that distinguishes different types of right-censoring events from a causal perspective, and demonstrate how this framework relates to censoring definitions and assumptions in classical survival analysis literature. By bridging these perspectives, we provide a clearer understanding of how to handle right-censoring events and provide guidance for identifying causal estimands when right-censored events are present.

On treating right-censoring events like treatments

TL;DR

The paper addresses how to handle right-censoring events in causal inference without requiring the elimination of all censoring to define estimands. It introduces a unified framework that distinguishes nuisance from non-nuisance right-censoring, formalizes two estimands and , and derives identification results under models and , clarifying when these estimands coincide. It connects the causal framework to classical survival analysis via conditional independent and discusses identity slippages when censoring interacts with outcomes. The work guides practitioners in selecting appropriate estimands and applying g-formula or proxy-based methods, with sensitivity analyses and extensions to broader estimands. Overall, it provides a principled approach to incorporating right-censoring into causal estimands rather than treating it solely as missing data.

Abstract

In causal inference literature, potential outcomes are often indexed by the "elimination of all right-censoring events," leading to the perception that such a restriction is necessary for defining well-posed causal estimands. In this paper, we clarify that this restriction is not required: a well-defined estimand can be formulated without indexing on the elimination of such events. Achieving this requires a more precise classification of right-censoring events than has historically been considered, as the nature of these events has direct implications for identification of the target estimand. We provide a framework that distinguishes different types of right-censoring events from a causal perspective, and demonstrate how this framework relates to censoring definitions and assumptions in classical survival analysis literature. By bridging these perspectives, we provide a clearer understanding of how to handle right-censoring events and provide guidance for identifying causal estimands when right-censored events are present.

Paper Structure

This paper contains 15 sections, 3 theorems, 6 equations, 7 figures, 1 table.

Key Result

Proposition 1

All nuisance right-censoring events are a subset of the set of observation-terminating events $\mathbf{C}_k$.

Figures (7)

  • Figure 1: Directed Acyclic Graph (DAG) depicting the factual data. For simplicity, we define two observation-terminating event $\mathbf{C}_k = (C_{k1},C_{k2})$. Note that we omit other arrows (e.g., $\mathbf L_0$ to $Y_{k-1}$) to reduce clutter, as adding omitted edges from past to future variables does not affect our assumptions.
  • Figure 2: Single World Intervention Graph (SWIG) depicting ($g,\overline{\mathbf{c}})$ potential variables (counterfactuals). For simplicity, we define two observation-terminating event $\mathbf{C}_k = (C_{k1},C_{k2})$. Note that we omit other arrows (e.g., $\mathbf L_0$ to $Y_{k-1}$) to reduce clutter, as adding omitted edges from past to future variables does not affect our assumptions.
  • Figure 3: Single World Intervention Graph (SWIG) depicting $g$ potential variables (counterfactuals). For simplicity, we define two observation-terminating event $\mathbf{C}_k = (C_{k1},C_{k2})$. Note that we omit other arrows (e.g., $\mathbf L_0$ to $Y_{k-1}$) to reduce clutter, as adding omitted edges from past to future variables does not affect our assumptions.
  • Figure 4: Directed Acyclic Graph (DAG) depicting the factual data, with right-censoring state added to Figure \ref{['fig:figure00']}. Bold arrows are used to emphasize deterministic relationships assumed herein.
  • Figure 5: Classification of right-censoring events relative to the estimands considered herein.
  • ...and 2 more figures

Theorems & Definitions (8)

  • Definition 1: Generalized definition of right-censoring event
  • Definition 2: Nuisance and non-nuisance right-censoring events
  • Proposition 1
  • Definition 3: Model $\mathcal{M}_1$
  • Proposition 2
  • Definition 4: Model $\mathcal{M}_2$
  • Proposition 3
  • Remark 1