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Spatial SIR epidemic model with varying infectivity in an unbounded domain: Law of Large Numbers

Armand Kanga, Etienne Pardoux

TL;DR

The paper studies a spatial SIR model with infectivity that depends on the age of infection and nonlocal transmission on an unbounded domain, with individuals fixed in space. It proves a law of large numbers for the empirical measures as the population size $N$ tends to infinity, yielding a deterministic limit described by a coupled system of integral equations for the susceptible, infectious, recovered compartments and the total infection force. The analysis hinges on a careful construction of measure-valued processes, a truncated deterministic framework on bounded domains $D_n$ to handle the unbounded setting, and rigorous well-posedness and convergence arguments. This provides a rigorous macroscopic description of spatial disease spread under nonlocal interactions and age-structured infectivity, applicable to large-scale or infinite spatial domains.

Abstract

We consider a spatial SIR epidemic model where the infectivity of infected individuals depends upon their age of infection, and infections are non local. The domain is an unbounded subset of $\R^d$,and the individuals do not move. We extend our earlier result in \cite{AK-EP}, where the domain was bounded, and prove a law of large numbers as the size of the population tends to $\infty$.

Spatial SIR epidemic model with varying infectivity in an unbounded domain: Law of Large Numbers

TL;DR

The paper studies a spatial SIR model with infectivity that depends on the age of infection and nonlocal transmission on an unbounded domain, with individuals fixed in space. It proves a law of large numbers for the empirical measures as the population size tends to infinity, yielding a deterministic limit described by a coupled system of integral equations for the susceptible, infectious, recovered compartments and the total infection force. The analysis hinges on a careful construction of measure-valued processes, a truncated deterministic framework on bounded domains to handle the unbounded setting, and rigorous well-posedness and convergence arguments. This provides a rigorous macroscopic description of spatial disease spread under nonlocal interactions and age-structured infectivity, applicable to large-scale or infinite spatial domains.

Abstract

We consider a spatial SIR epidemic model where the infectivity of infected individuals depends upon their age of infection, and infections are non local. The domain is an unbounded subset of ,and the individuals do not move. We extend our earlier result in \cite{AK-EP}, where the domain was bounded, and prove a law of large numbers as the size of the population tends to .

Paper Structure

This paper contains 4 sections, 15 theorems, 86 equations.

Key Result

Proposition 2.1

For all $\varphi \in C_b(D)$, $\left\{\overline{\mu}_t^{N}, \overline{\mu}_t^{S,N},\overline{\mu}_t^{\mathfrak{F},N},\overline{\mu}_t^{I,N}, \overline{\mu}_t^{R,N}, t\geq 0 \right\}$ satisfies

Theorems & Definitions (27)

  • Proposition 2.1
  • Lemma 3.1
  • proof
  • Lemma 3.2
  • proof
  • Theorem 3.1
  • Proposition 3.1
  • Lemma 3.3
  • proof
  • Lemma 3.4
  • ...and 17 more