Artificially intelligent agents in the social and behavioral sciences: A history and outlook
Petter Holme, Milena Tsvetkova
TL;DR
The paper traces a 75-year history of agentic AI in the social and behavioral sciences, from early computer simulations to modern generative AI, emphasizing bidirectional influence between AI innovations and scientific practice. It argues that AI serves as both a tool and a subject of study, shaping methods, theories, and ethical considerations, while social sciences, in turn, guide AI development. The work maps the progression through simulations, cybernetics, complexity science, big data, and GenAI, highlighting methodological shifts toward prediction, causal inference, and human-AI interactions. It concludes with a forward-looking outlook on how human-AI co-evolution will redefine knowledge production, with attention to replication, governance, and epistemic responsibilities.
Abstract
We review the historical development and current trends of artificially intelligent agents (agentic AI) in the social and behavioral sciences: from the first programmable computers, and social simulations soon thereafter, to today's experiments with large language models. This overview emphasizes the role of AI in the scientific process and the changes brought about, both through technological advancements and the broader evolution of science from around 1950 to the present. Some of the specific points we cover include: the challenges of presenting the first social simulation studies to a world unaware of computers, the rise of social systems science, intelligent game theoretic agents, the age of big data and the epistemic upheaval in its wake, and the current enthusiasm around applications of generative AI, and many other topics. A pervasive theme is how deeply entwined we are with the technologies we use to understand ourselves.
