GUIDE: Towards Scalable Advising for Research Ideas
Yaowenqi Liu, Bingxu Meng, Rui Pan, Yuxing Liu, Jerry Huang, Jiaxuan You, Tong Zhang
TL;DR
GUIDE presents a scalable, retrieval-augmented framework for hypothesis evaluation and experimental design guidance. By compressing literature into modular summaries and enforcing rubric-guided alignment via RAFT, a relatively small model (GUIDE-7B) outperforms larger general-purpose LLMs on ICLR 2025 acceptance predictions, especially when predictions are high-confidence. The approach combines four components—Guidelines, Understanding, Information Retrieval, Direction, and Explanation—into a structured feedback loop that reduces hallucinations and improves actionable critique. Empirical results show strong Top-30% precision and high-confidence performance, with ablations demonstrating the value of modular summarization, rubrics, and uncertainty-aware selection. The work suggests a promising path for scalable, domain-aware AI advising systems that can meaningfully augment scientific ideation and decision-making.
Abstract
The field of AI research is advancing at an unprecedented pace, enabling automated hypothesis generation and experimental design across diverse domains such as biology, mathematics, and artificial intelligence. Despite these advancements, there remains a significant gap in the availability of scalable advising systems capable of providing high-quality, well-reasoned feedback to refine proposed hypotheses and experimental designs. To address this challenge, we explore key factors that underlie the development of robust advising systems, including model size, context length, confidence estimation, and structured reasoning processes. Our findings reveal that a relatively small model, when equipped with a well-compressed literature database and a structured reasoning framework, can outperform powerful general-purpose language models such as Deepseek-R1 in terms of acceptance rates for self-ranked top-30% submissions to ICLR 2025. Moreover, when limited to high-confidence predictions, our system achieves an acceptance rate exceeding 90% on the ICLR 2025 test set, underscoring its potential to significantly enhance the quality and efficiency of hypothesis generation and experimental design. The code is released at https://github.com/HowardLiu0830/GUIDE-Research-Idea-Evaluation.
