Privacy-Preserving in Medical Image Analysis: A Review of Methods and Applications
Yanming Zhu, Xuefei Yin, Alan Wee-Chung Liew, Hui Tian
TL;DR
This paper surveys privacy-preserving techniques for medical image analysis, addressing the tension between data utility and patient privacy. It frameworks privacy methods—encryption, differential privacy, federated learning, homomorphic encryption, and GAN-based synthetic data—across diagnosis, pathology, and telemedicine tasks, and discusses emerging trends such as zero-knowledge proofs and secure multi-party computation. The contributions include organizing methods by application-specific challenges, evaluating advantages and limitations, and outlining future directions for adaptable, scalable privacy frameworks. The work aims to guide researchers and practitioners toward practical deployment of privacy-preserving AI in medical imaging, enabling safer data sharing and robust clinical AI.
Abstract
With the rapid advancement of artificial intelligence and deep learning, medical image analysis has become a critical tool in modern healthcare, significantly improving diagnostic accuracy and efficiency. However, AI-based methods also raise serious privacy concerns, as medical images often contain highly sensitive patient information. This review offers a comprehensive overview of privacy-preserving techniques in medical image analysis, including encryption, differential privacy, homomorphic encryption, federated learning, and generative adversarial networks. We explore the application of these techniques across various medical image analysis tasks, such as diagnosis, pathology, and telemedicine. Notably, we organizes the review based on specific challenges and their corresponding solutions in different medical image analysis applications, so that technical applications are directly aligned with practical issues, addressing gaps in the current research landscape. Additionally, we discuss emerging trends, such as zero-knowledge proofs and secure multi-party computation, offering insights for future research. This review serves as a valuable resource for researchers and practitioners and can help advance privacy-preserving in medical image analysis.
