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BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): II. 2-year Neurocognitive Outcome and NICU Outcome

Rina Bao, Yangming Ou

TL;DR

The second release of the Boston Neonatal Brain Injury Dataset for Hypoxic-Ischemic Encephalopathy (BONBID-HIE), an open-source, comprehensive MRI and clinical dataset featuring 237 patients, including NICU outcomes and 2-year neurocognitive outcomes from Massachusetts General Hospital and Boston Children's Hospital is introduced.

Abstract

Hypoxic Ischemic Encephalopathy (HIE) affects approximately 1-5/1000 newborns globally and leads to adverse neurocognitive outcomes in 30% to 50% of cases by two years of age. Despite therapeutic advances with Therapeutic Hypothermia (TH), prognosis remains challenging, highlighting the need for improved biomarkers. This paper introduces the second release of the Boston Neonatal Brain Injury Dataset for Hypoxic-Ischemic Encephalopathy (BONBID-HIE), an open-source, comprehensive MRI and clinical dataset featuring 237 patients, including NICU outcomes and 2-year neurocognitive outcomes from Massachusetts General Hospital and Boston Children's Hospital.

BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): II. 2-year Neurocognitive Outcome and NICU Outcome

TL;DR

The second release of the Boston Neonatal Brain Injury Dataset for Hypoxic-Ischemic Encephalopathy (BONBID-HIE), an open-source, comprehensive MRI and clinical dataset featuring 237 patients, including NICU outcomes and 2-year neurocognitive outcomes from Massachusetts General Hospital and Boston Children's Hospital is introduced.

Abstract

Hypoxic Ischemic Encephalopathy (HIE) affects approximately 1-5/1000 newborns globally and leads to adverse neurocognitive outcomes in 30% to 50% of cases by two years of age. Despite therapeutic advances with Therapeutic Hypothermia (TH), prognosis remains challenging, highlighting the need for improved biomarkers. This paper introduces the second release of the Boston Neonatal Brain Injury Dataset for Hypoxic-Ischemic Encephalopathy (BONBID-HIE), an open-source, comprehensive MRI and clinical dataset featuring 237 patients, including NICU outcomes and 2-year neurocognitive outcomes from Massachusetts General Hospital and Boston Children's Hospital.

Paper Structure

This paper contains 13 sections, 2 figures, 2 tables.

Figures (2)

  • Figure 1: Representative cases for 4 HIE patients from MGH and BCH. For each patient, in the upper panel: apparent diffusion coefficient (ADC) maps; in the bottom panel: $Z_{ADC}$ maps.
  • Figure 2: Folder structure of the BONBID-HIE dataset (Part II. NICU outcome and neurocognitive outcome).