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Process-Aware Analysis of Treatment Paths in Heart Failure Patients: A Case Study

Harry H. Beyel, Marlo Verket, Viki Peeva, Christian Rennert, Marco Pegoraro, Katharina Schütt, Wil M. P. van der Aalst, Nikolaus Marx

TL;DR

This case study applies process-mining techniques on sparse patient heart failure data and applies decision mining to determine whether a patient will have a cardiovascular outcome and whether a patient will die.

Abstract

Process mining in healthcare presents a range of challenges when working with different types of data within the healthcare domain. There is high diversity considering the variety of data collected from healthcare processes: operational processes given by claims data, a collection of events during surgery, data related to pre-operative and post-operative care, and high-level data collections based on regular ambulant visits with no apparent events. In this case study, a data set from the last category is analyzed. We apply process-mining techniques on sparse patient heart failure data and investigate whether an information gain towards several research questions is achievable. Here, available data are transformed into an event log format, and process discovery and conformance checking are applied. Additionally, patients are split into different cohorts based on comorbidities, such as diabetes and chronic kidney disease, and multiple statistics are compared between the cohorts. Conclusively, we apply decision mining to determine whether a patient will have a cardiovascular outcome and whether a patient will die.

Process-Aware Analysis of Treatment Paths in Heart Failure Patients: A Case Study

TL;DR

This case study applies process-mining techniques on sparse patient heart failure data and applies decision mining to determine whether a patient will have a cardiovascular outcome and whether a patient will die.

Abstract

Process mining in healthcare presents a range of challenges when working with different types of data within the healthcare domain. There is high diversity considering the variety of data collected from healthcare processes: operational processes given by claims data, a collection of events during surgery, data related to pre-operative and post-operative care, and high-level data collections based on regular ambulant visits with no apparent events. In this case study, a data set from the last category is analyzed. We apply process-mining techniques on sparse patient heart failure data and investigate whether an information gain towards several research questions is achievable. Here, available data are transformed into an event log format, and process discovery and conformance checking are applied. Additionally, patients are split into different cohorts based on comorbidities, such as diabetes and chronic kidney disease, and multiple statistics are compared between the cohorts. Conclusively, we apply decision mining to determine whether a patient will have a cardiovascular outcome and whether a patient will die.
Paper Structure (13 sections, 3 figures, 9 tables)

This paper contains 13 sections, 3 figures, 9 tables.

Figures (3)

  • Figure 1: Overview of our work.
  • Figure 2: De-facto model of treatment paths.
  • Figure 3: De-jure model of treatment paths.

Theorems & Definitions (7)

  • Definition 1: Event Log
  • Definition 2: Patient Data and Sequences
  • Definition 3: Sequence Before and After Outcome
  • Definition 4: Transformation Before Outcome
  • Definition 5: Transformation After Outcome
  • Definition 6: Occurrence count: case
  • Definition 7: Occurrence count: event log