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Holographic Phase Retrieval and Reference Design

David A. Barmherzig, Ju Sun, T. J. Lane, Po-Nan Li, Emmanuel J. Candès

TL;DR

The paper addresses holographic phase retrieval by introducing a framework that integrates a known reference into coherent diffraction imaging, converting the reconstruction into a linear deconvolution problem. It formulates the Referenced Deconvolution algorithm, derives an explicit error expression under Poisson shot noise, and introduces a reference-scaling factor to compare reference choices. Through analysis of three canonical references (pinhole, slit, block), it shows how spectral weighting differs across references and demonstrates optimality swings depending on the signal spectrum, with numerical simulations validating the theory. The findings offer a practical design perspective for reference selection in CDI, enabling faster, provably reliable reconstructions under realistic noise, and motivate extensions such as dual-reference designs and beamstop accommodations.

Abstract

A general mathematical framework and recovery algorithm is presented for the holographic phase retrieval problem. In this problem, which arises in holographic coherent diffraction imaging, a "reference" portion of the signal to be recovered via phase retrieval is a priori known from experimental design. A generic formula is also derived for the expected recovery error when the measurement data is corrupted by Poisson shot noise. This facilitates an optimization perspective towards reference design and analysis. We employ this optimization perspective towards quantifying the performance of various reference choices.

Holographic Phase Retrieval and Reference Design

TL;DR

The paper addresses holographic phase retrieval by introducing a framework that integrates a known reference into coherent diffraction imaging, converting the reconstruction into a linear deconvolution problem. It formulates the Referenced Deconvolution algorithm, derives an explicit error expression under Poisson shot noise, and introduces a reference-scaling factor to compare reference choices. Through analysis of three canonical references (pinhole, slit, block), it shows how spectral weighting differs across references and demonstrates optimality swings depending on the signal spectrum, with numerical simulations validating the theory. The findings offer a practical design perspective for reference selection in CDI, enabling faster, provably reliable reconstructions under realistic noise, and motivate extensions such as dual-reference designs and beamstop accommodations.

Abstract

A general mathematical framework and recovery algorithm is presented for the holographic phase retrieval problem. In this problem, which arises in holographic coherent diffraction imaging, a "reference" portion of the signal to be recovered via phase retrieval is a priori known from experimental design. A generic formula is also derived for the expected recovery error when the measurement data is corrupted by Poisson shot noise. This facilitates an optimization perspective towards reference design and analysis. We employ this optimization perspective towards quantifying the performance of various reference choices.

Paper Structure

This paper contains 34 sections, 13 theorems, 77 equations, 10 figures, 1 algorithm.

Key Result

Lemma 2.1

$Y = AXB \Longleftrightarrow \mathop{\mathrm{vec}}\nolimits(Y)=(B^T \otimes A)\mathop{\mathrm{vec}}\nolimits(X)$.

Figures (10)

  • Figure 1: CDI setup. Image courtesy of Candes-PL-Masks.
  • Figure 2: Holographic CDI setup. Image courtesy of FT-Cambridge.
  • Figure 3: The diffraction area in Holographic CDI contains an unknown specimen (here shown as a mimivirus Mimivirus) together with a known reference (here shown as "$\boldsymbol{\mathrm{R}}$"). Popular choices for the reference $\boldsymbol{\mathrm{R}}$ are shown in \ref{['fig:ref-compar']}.
  • Figure 4: Schematic of the three leading reference choices for Holographic CDI. (Images have $16 \times 16$ enlarged pixels for illustration.)
  • Figure 5: Transmission coefficient of polycarbonate at different photon energies transm.
  • ...and 5 more figures

Theorems & Definitions (22)

  • Lemma 2.1
  • Definition 2.2
  • Definition 2.3
  • Example 2.4
  • Remark 2.6
  • Lemma 2.7: trench
  • Definition 2.8
  • Definition 2.9
  • Definition 2.10
  • Definition 3.1
  • ...and 12 more